Fig. 1.

Model fit to fractional tumor size for standard radiation sensitivity with cold effect. a Fractional volumes vs time: measured relative tumor volumes (dots), relative tumor size calculation (dark line), cell survival (dashed line), and fraction cleared (thin line). b Averaged equivalent dose vs time: cumulative absorbed dose (dark line), cold effect (thin line), proliferation (dotted line), BET/α (medium dark line), EUD (horizontal dashed line), p13, α=0.28 Gy⁻¹, λ_p=0.046 g_T/mg_P/h