Inhibition of DNMT interferes with contextual fear memory. A, Diagram outlines the experimental design used with data presented in B. B, On test day 1, zebularine- or RG108-treated animals exhibited lower amounts of freezing behavior compared with vehicle-treated animals (zebularine, t(9) = 2.52, p = 0.0328; RG108, t(8) = 3.72, p = 0.0059, n = 9–10; Student's t test, *p < 0.05, **p < 0.01). Error bars indicate SEM.