Table 1.

Splenic CD4+ T cells and B-cell subsets in NOD.H-2h4 mice vary with age

Age (weeks)	CD4	CD19	FO	MZ	T2	T1
2	5.0 ± 0.8	61.0 ± 4.6	19.1 ± 4.3	2.6 ± 0.5	2.6 ± 1.6	41.3 ± 6.4
3	7.4 ± 1.0	50.4 ± 4.1	33.0 ± 1.8	5.1 ± 1.8	2.7 ± 0.9	29.3 ± 5.1
4–5	11.6 ± 1.9	55.8 ± 3.7	32.2 ± 6.7	9.8 ± 2.2	4.9 ± 2.0	24.5 ± 7.0
7–8	22.0 ± 1.6	47.1 ± 2.5	37.2 ± 1.9	16.6 ± 2.7	6.0 ± 0.5	11.1 ± 1.5

Mean percentages of positive cells ± SEM for six to eight individual mice. The percentage of each B-cell subset is expressed as a percentage of B220+ cells (see Methods).