Table 2.
Multiple Logistic Regression Models Testing the Relationship of the 5 BP Variables With the Likelihood of Having AD in the Cross-Sectional Examination
Systolic pressure, N = 1823 | Diastolic pressure, N = 1823 | Pulse pressure, N = 1823 | Mean arterial pressure, N = 1823 | Self-reported hypertension, N = 1732 | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | |
BP variable | 1.00 | 0.99-1.00 | .095 | 1.00 | 0.99-1.01 | .429 | 1.00 | 0.99--1.00 | .145 | 0.99 | 0.99-1.00 | .162 | 0.87 | 0.70-1.09 | .236 |
Age, y | 1.03 | 1.02-1.05 | <.001 | 1.03 | 1.02-1.04 | <.001 | 1.03 | 1.02-1.05 | <.001 | 1.03 | 1.02-1.04 | <.001 | 1.03 | 1.02-1.05 | <.001 |
Education, y | 0.87 | 0.85-0.90 | <.001 | 0.88 | 0.85-0.91 | <.001 | 0.88 | 0.85-0.90 | <.001 | 0.88 | 0.85-0.90 | <.001 | 0.87 | 0.85-0.90 | <.001 |
AA vs Caucasian | 1.62 | 1.10-2.39 | .024 | 1.59 | 1.08-2.35 | .018 | 1.62 | 1.10-2.38 | .015 | 1.61 | 1.09-2.37 | .016 | 1.40 | 0.94-2.01 | .099 |
Male vs female | 1.34 | 1.08-1.67 | .009 | 1.34 | 1.08-1.67 | .009 | 1.34 | 1.07-1.67 | .010 | 1.35 | 1.08-1.67 | .009 | 1.37 | 1.10-1.72 | .006 |
APOE-ϵ4(+) | 3.04 | 2.47-3.80 | <.001 | 3.04 | 2.44-3.80 | <.001 | 3.04 | 2.44-3.80 | <.001 | 3.04 | 2.44-3.80 | <.001 | 3.16 | 2.51-3.98 | <.001 |
APOE-ϵ2(+) | 0.67 | 0.48-0.92 | .015 | 0.67 | 0.49-0.93 | .016 | 0.67 | 0.48-0.93 | .015 | 0.67 | 0.49-0.93 | .015 | 0.70 | 0.51-0.99 | .045 |
Abbreviations: CI, confidence interval; OR, odds ratio; AA, African American; APOE, apolipoprotein E; BP, blood pressure.