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. 2012 Mar 7;2012:842632. doi: 10.1155/2012/842632

Figure 6.

Figure 6

PETN-induced enhancement of the human HO-1 promoter activity depends on NRF2. DLD1-HO-11kb-Prom cells were transfected with a specific anti-NRF2 siRNA (siNRF2) or a nonrelated control siRNA (siCon). After 48 h, the cells were incubated with PETN or the solvent DMSO. Extracts were prepared and luciferase activity and protein content were measured, and luciferase activity was normalized to the protein content. Shown (mean ± SEM; n = 5-6) are the normalized luciferase activity values. The normalized luciferase activity of the cell treated with solvent and siCon was set to 100%. (**= P < 0.01, *= P < 0.05, ns: not significant different to DMSO and siCon-treated cells. Modified from [34].