Table 1.
Known and putative TFs of the AraC/XylS family identified by a structural similarity search in the PDB.
| Name (PDB code) | UniProt ID | DNA complex(a) | Technique (Res.)(b) | Species | Biological process |
|---|---|---|---|---|---|
| MarA (1bl0) | P0ACH5 | Yes | X-ray (2.30 Å) | Escherichia coli | Multiple antibiotic resistance |
| MarA (1xs9) | P0ACH5 | Yes | NMR | Escherichia coli | Multiple antibiotic resistance |
| Rob (1d5y) | P0ACI0 | Yes | X-ray (2.70 Å) | Escherichia coli | Antibiotic resistance, organic solvent tolerance and heavy-metal resistance |
| Ada (1u8b) | P06134 | Yes | X-ray (2.10 Å) | Escherichia coli | Repair of and response to alkylated DNA |
| Ada (1zgw) | P06134 | Yes | NMR | Escherichia coli | Repair of and response to alkylated DNA |
| Ada (1wpk) | P06134 | No | NMR | Escherichia coli | Repair of and response to alkylated DNA |
| GadX (3mkl) | B1X7X1 | No | X-ray (2.15 Å) | Escherichia coli | Acid resistance |
| AraC (2k9s) | P0A9E0 | No | NMR | Escherichia coli | Transport and catabolism of L-arabinose |
| TcpN or ToxT (3gbg) | A5F384 | No | X-ray (1.90 Å) | Vibrio cholerae | Biosynthesis and assembly of the toxin-coregulated pilus |
| YesN (3lsg) | Q8RGT8 | No | X-ray (2.05 Å) | Fusobacterium nucleatum | Possibly involved in plant cell wall degradation |
| Lin2118 protein (3oou) | Q92A04 | No | X-ray (1.57 Å) | Listeria innocua | Unknown |
| 3oio | Q7NTG7 | No | X-ray (1.65 Å) | Chromobacterium violaceum | Unknown |
| 3mn2 | Q6NCA5 | No | X-ray (1.80 Å) | Rhodopseudomonas palustris | Unknown |
(a)Indicates whether the 3D protein structure was cocrystallized with DNA or not.
(b)Numbers in parenthesis refer to the resolution of crystal structures.