Table 2. Adsorption, distribution, metabolism, toxicity properties and predicted pIC₅₀ of Saracatinib and the top three TCM compounds.

Name	ADMET Adsorption Level1	PPBLevel2	CYP2D6Probability3	Hepatoxicity4	Bioactivity Prediction (pIC50)
					SVM	MLR
Isopraeroside IV	1	2	0.356	0	6.0277	7.7282
9HFG	1	2	0.297	0	6.8590	7.5342
Aurantiamide	0	2	0.475	0	4.6490	4.4080
Saracatinib*	0	0	0.297	0	7.3036	4.9410

^*Control.

¹ADMET Adsorption levels: 0 = Good; 1 = Moderate; 2 = Low; 3 = Very low.

²Plasma Protein Binding: 0 = Binding <90% ;1 = Binding >90%; 2 = Binding >95%.

³Inhibition probability of Cytochrome P450 2D6 enzyme.

⁴Hepatoxicity: 0 = Nontoxic; 1 = Toxic.