Table 2. In vitro fungicidal activity of the selected Fc-peptides against fungal strains.
| Fungicidal activity | ||||||
| N10K | T11F | H4L | ||||
| Fungal strain | %* | EC50 **(95% confidence intervals) [mol/liter]×10−6 | % | EC50 (95% confidence intervals) [mol/liter]×10−6 | % | EC50 |
| C. albicans SC5314 | 100 | 1.004 (0.947–1.065) | 100 | 1.540 (1.404–1.689) | 84.34 | n.d. |
| C. albicans CA-6 | 100 | 2.939 (2.578–3.351) | 100 | 0.518 (0.506–0.531) | 57.04 | n.d. |
| C. albicans SA40 | 100 | 1.763 (1.670–1.861) | 100 | 0.286 (0.251–0.326) | 55.99 | n.d. |
| C. albicans AIDS68 | 100 | 1.745 (1.396–2.180) | 100 | 0.295 (0.254–0.341) | 59.82 | n.d. |
| C. albicans UM4 | 100 | 2.784 (2.622–2.956) | 100 | 0.667 (0.636–0.700) | 64.63 | n.d. |
| C. glabrata OMNI32 | 100 | 3.584 (3.390–3.788) | 100 | 0.252 (0.245–0.260) | 80.49 | n.d. |
| C. neoformans 6995 | 100 | 2.948 (2.645–3.288) | 100 | 0.811 (0.632–1.041) | 85.08 | n.d. |
| M. furfur 101 | 100 | 2.833 (1.900–4.226) | 100 | 0.115 (0.103–0.129) | 92.04 | n.d. |
*
% inhibitory activity at 100 µg/ml in comparison to the control growth (water);
**
EC50, half maximal effective concentration;
n.d., not determined.