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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Osteoarthritis Cartilage. 2011 May 12;19(7):864–873. doi: 10.1016/j.joca.2011.04.011

Figure 3.

Figure 3

Chondrocyte cell death as assessed by NBT nuclear stain (n=3 per group per timepoint). Vertical bars denote ± 95% CI. A. The total joint score (maximum possible total joint score = 20) of cell death was greater in the fractured experimental limb than the contralateral control limb in both the anterior and central regions of the knee joint (*p=0.014 for anterior region, p=0.016 for central region). B. Cell death by location in the joint (maximum possible site score = 5) was greater in the fractured experimental limb than the contralateral control limb (* p=0.003 for lateral femur, p=0.04 for medial femur, p=0.001 for lateral tibia), and cell death was significantly greater in the lateral tibial than the medial tibia in the fractured experimental limb (p=0.0002) for the anterior region of the knee. For all measures of chondrocyte cell death there was no significant difference between low energy and high energy fractures.