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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Osteoarthritis Cartilage. 2011 May 12;19(7):864–873. doi: 10.1016/j.joca.2011.04.011

Table 1.

Grading scheme for assessment of chondrocyte viability in the mouse knee joint from nitroblue tetrazolium (NBT) staining in viable cells. Maximum possible site score of 5 for the medial and lateral femoral condyles and tibial plateau. Maximum possible total joint score of 20 summed from site scores for each joint.

Grade Description
0 ≥ 95% viable cells in all of plateau or condyle
1 cell death in < ½ plateau or condyle, < ½ depth
2 cell death in < ½ plateau or condyle, ≥ ½ depth
3 cell death in ≥ ½ plateau or condyle, < ½ depth
4 cell death in ≥ ½ plateau or condyle, ≥ ½ depth
5 < 10% viable cells in all of plateau or condyle