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Synthetic schemes for the 3,6,9-trisubstituted acridine derivatives 3 and 4. The individual steps involved (i) KNO3/H2SO4, (ii) CrO3, AcOH, reflux, (iii) Zn/HCl, 90–100°C, (iv) 3-CPC, reflux, (v) NHR2, EtOH, NaI, reflux, (vi) HCl, (vii) POCl3, reflux, and (viii) H2NPhNR2, CHCl3, rt.
