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Upregulation of renal preproET-1 and ETA receptor in the eNOS−/− mice with excess sFlt-1. mRNA levels of (A) preproET-1 and (B) ETA receptor in the kidney of WT and eNOS−/− mice administered with Ad Fc or Ad sFlt-1. RNA was prepared from the whole kidney. n≥5 for each group.
