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Subcellular localization of U1 snRNA in cells where the expression of nuclear speckle proteins was repressed by RNAi. FISH analyses of HeLa-TO cells transfected with the indicated siRNAs (endogenous U1 snRNA, green) are displayed, together with immunocytochemical staining of SRSF2 (SC35) (red), SRm300 (cyan), and DAPI staining of DNA (blue).
