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Influence of the HIV Tat peptide on the folding of TAR RNA (Puglisi et al. 1992). (A) Secondary structure of TAR RNA; (B) NMR structure of the free TAR RNA; (C) NMR structure of the TAR RNA bound to a nine-amino acid peptide from Tat protein or bound to a single argininamide (shown). The argininamide is shown in orange and the three-nucleotide bulge loop in dark blue.
