Table 1.
Average Baseline Values of the Calcium-Related Metabolitesa
| Placebo | PPI | Differenceb | p Valuec | |
|---|---|---|---|---|
| Serum minerals (mmol/L) | ||||
| Calcium | 2.41 ± 0.06 | 2.38 ± 0.07 | −0.03 ± 0.07 | .19 |
| Ionized calcium | 1.27 ± 0.03 | 1.25 ± 0.03 | −0.02 ± 0.05 | .20 |
| Serum hormones (pmol/L) | ||||
| Midmolecule PTH | 35.1 ± 8.5 | 35.6 ± 10.6 | 0.6 ± 7.0 | .79 |
| 1,25(OH)2D3 | 142.0 ± 34.8 | 136.6 ± 28.0 | −5.4 ± 19.3 | .35 |
| 24-hour urine (mmol) | ||||
| Sodium | 83.3 ± 36.8 | 79.3 ± 29.8 | −4.4 ± 47.8 | .76 |
| Calcium | 3.88 ± 1.88 | 4.16 ± 2.34 | 0.28 ± 1.46 | .53 |
| GFR (mL/min) | 117.3 ± 26.8 | 118.8 ± 33.0 | 1.5 ± 23.2 | .83 |
| Ca/kgd | 2.15 ± 1.20 | 2.26 ± 1.45 | 0.11 ± 1.13 | .75 |
| Calcium/creatininee | 0.17 ± 0.26 | 0.11 ± 0.04 | −0.07 ± 0.26 | .39 |
a
All variables are presented as mean ± SD.
b
Mean change between placebo and PPI as mean ± SD.
c
Two-tailed paired t test between placebo and PPI baseline values.
d
Ca/kg =urinary calcium (mg/day)/body weight (kg).
e
Calcium:creatinine =urinary calcium (mg/day)/urinary creatinine (mg/day).