Table 1.
HP (n = 26) | NP (n =21) | p Value | |||||
---|---|---|---|---|---|---|---|
Baseline | 12 months | Baseline | 12 months | Diet | Time | Diet × Time | |
Age (years) | 58.5 ± 4.1 | 57.4 ± 4.7 | |||||
Weight (kg) | 88.5 ± 15.1 | 82.8 ± 15.4 | 82.7 ± 12.2 | 76.6 ± 11.7 | .151 | <.001 | .755 |
Fat mass (kg) | 39.6 ± 9.5 | 35.4 ± 10.6 | 36.9 ± 8.4 | 32.4 ± 8.3 | .321 | <.001 | .834 |
Lean mass (kg) | 45.2 ± 6.4 | 44.0 ± 5.8 | 41.7 ± 5.5 | 40.3 ± 4.6 | .034 | <.001 | .504 |
BMD (g/cm2) | |||||||
UD radius | 0.37 ± 0.05 | 0.37 ± 0.05 | 0.37 ± 0.07 | 0.36 ± 0.06 | .837 | .002 | .032 |
1/3 radius | 0.69 ± 0.06 | 0.68 ± 0.06 | 0.68 ± 0.08 | 0.67 ± 0.08 | .419 | .012 | .490 |
Lumbar spinea | 1.24 ± 0.17 | 1.25 ± 0.18 | 1.13 ± 0.17 | 1.12 ± 0.17 | .063 | .193 | .028 |
Trochanter | 0.82 ± 0.11 | 0.82 ± 0.12 | 0.75 ± 0.09 | 0.74 ± 0.10 | .032 | .287 | .512 |
Femoral neck | 0.94 ± 0.10 | 0.94 ± 0.11 | 0.89 ± 0.10 | 0.89 ± 0.10 | .085 | .887 | .884 |
Total hip | 1.02 ± 0.12 | 1.01 ± 0.12 | 0.94 ± 0.01 | 0.93 ± 0.10 | .020 | .004 | .050 |
Total body | 1.20 ± 0.09 | 1.19 ± 0.09 | 1.14 ± 0.10 | 1.12 ± 0.10 | .023 | .007 | .951 |
BMC (g) | |||||||
UD radius | 1.31 ± 0.19 | 1.28 ± 0.19 | 1.28 ± 0.21 | 1.28 ± 0.20 | .846 | .246 | .119 |
1/3 radius | 1.67 ± 0.20 | 1.69 ± 0.23 | 1.61 ± 0.26 | 1.61 ± 0.26 | .289 | .553 | .591 |
Lumbar spine | 54.0 ± 11.3 | 54.3 ± 12.1 | 46.5 ± 9.7 | 46.1 ± 9.6 | .047 | .009 | .469 |
Trochanter | 10.1 ± 2.1 | 10.3 ± 2.1 | 9.0 ± 1.6 | 9.3 ± 1.9 | .047 | .354 | .739 |
Femoral neck | 5.0 ± 0.7 | 4.9 ± 0.7 | 4.4 ± 0.6 | 4.4 ± 0.5 | .003 | .042 | .706 |
Total hip | 32.1 ± 3.9 | 32.0 ± 4.0 | 29.1 ± 3.3 | 29.0 ± 3.5 | .007 | .661 | .930 |
Total body | 2523 ± 299 | 2520 ± 338 | 2352 ± 408 | 2340 ± 357 | .058 | .258 | .177 |
Values are mean ± SD (all variables); UD =ultra distal radius.
16 subjects had their lumbar spine BMD scans reanalyzed according to ISCD exclusion criteria.
A two-factor repeated-measures ANOVA was performed with time (0, 6, and 12 months) and diet (HP or NP) as independent variables.