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. 2010 Dec 16;26(6):1339–1348. doi: 10.1002/jbmr.318

Table 1.

Body Composition, Bone Mineral Density, and Content Over 12 Months in the Two Treatment Groupsa,b

HP (n = 26) NP (n =21) p Value



Baseline 12 months Baseline 12 months Diet Time Diet × Time
Age (years) 58.5 ± 4.1 57.4 ± 4.7
Weight (kg) 88.5 ± 15.1 82.8 ± 15.4 82.7 ± 12.2 76.6 ± 11.7 .151 <.001 .755
Fat mass (kg) 39.6 ± 9.5 35.4 ± 10.6 36.9 ± 8.4 32.4 ± 8.3 .321 <.001 .834
Lean mass (kg) 45.2 ± 6.4 44.0 ± 5.8 41.7 ± 5.5 40.3 ± 4.6 .034 <.001 .504
BMD (g/cm2)
 UD radius 0.37 ± 0.05 0.37 ± 0.05 0.37 ± 0.07 0.36 ± 0.06 .837 .002 .032
 1/3 radius 0.69 ± 0.06 0.68 ± 0.06 0.68 ± 0.08 0.67 ± 0.08 .419 .012 .490
 Lumbar spinea 1.24 ± 0.17 1.25 ± 0.18 1.13 ± 0.17 1.12 ± 0.17 .063 .193 .028
 Trochanter 0.82 ± 0.11 0.82 ± 0.12 0.75 ± 0.09 0.74 ± 0.10 .032 .287 .512
 Femoral neck 0.94 ± 0.10 0.94 ± 0.11 0.89 ± 0.10 0.89 ± 0.10 .085 .887 .884
 Total hip 1.02 ± 0.12 1.01 ± 0.12 0.94 ± 0.01 0.93 ± 0.10 .020 .004 .050
 Total body 1.20 ± 0.09 1.19 ± 0.09 1.14 ± 0.10 1.12 ± 0.10 .023 .007 .951
BMC (g)
 UD radius 1.31 ± 0.19 1.28 ± 0.19 1.28 ± 0.21 1.28 ± 0.20 .846 .246 .119
 1/3 radius 1.67 ± 0.20 1.69 ± 0.23 1.61 ± 0.26 1.61 ± 0.26 .289 .553 .591
 Lumbar spine 54.0 ± 11.3 54.3 ± 12.1 46.5 ± 9.7 46.1 ± 9.6 .047 .009 .469
 Trochanter 10.1 ± 2.1 10.3 ± 2.1 9.0 ± 1.6 9.3 ± 1.9 .047 .354 .739
 Femoral neck 5.0 ± 0.7 4.9 ± 0.7 4.4 ± 0.6 4.4 ± 0.5 .003 .042 .706
 Total hip 32.1 ± 3.9 32.0 ± 4.0 29.1 ± 3.3 29.0 ± 3.5 .007 .661 .930
 Total body 2523 ± 299 2520 ± 338 2352 ± 408 2340 ± 357 .058 .258 .177

Values are mean ± SD (all variables); UD =ultra distal radius.

a

16 subjects had their lumbar spine BMD scans reanalyzed according to ISCD exclusion criteria.

b

A two-factor repeated-measures ANOVA was performed with time (0, 6, and 12 months) and diet (HP or NP) as independent variables.