Table 2.
Trabecular and Cortical Volumetric BMD, BMC, and Geometry Over 12 Months in the Two Treatment Groupsa,b
| HP (n =26) | NP (n =21) | p Valueb | |||||
|---|---|---|---|---|---|---|---|
| Baseline | 12 months | Baseline | 12 months | Diet | Time | Diet × Time | |
| Total BMC (mg) | 301.3 ± 40.5 | 304.8 ± 46.4 | 280.1 ± 36.1 | 276.2 ± 32.5 | .036 | .718 | .061 |
| Total vBMD (mg/cm3) | 298.8 ± 33.3 | 296.9 ± 34.3 | 306.8 ± 45.7 | 295.8 ± 40.2 | .679 | .031 | .049 |
| Trabecular BMC (mg) | 104.0 ± 18.8 | 110.9 ± 26.6 | 97.1 ± 20.3 | 95.3 ± 16.8 | .083 | .581 | .043 |
| Trabecular BMD (mg/cm3) | 228.6 ± 31.7 | 232.9 ± 33.8 | 237.6 ± 58.7 | 225.2 ± 32.4 | .831 | .207 | .041 |
| Total area (mm2) | 1012.3 ± 117.0 | 1036.3 ± 161.9 | 926.4 ± 134.2 | 945.2 ± 128.6 | .021 | .026 | .700 |
| Cortical BMC (mg) | 325.5 ± 31.6 | 325.6 ± 31.2 | 294.7 ± 41.2 | 291.9 ± 40.8 | .005 | .423 | .173 |
| Cortical volumetric BMD (mg/cm3) | 1147.1 ± 27.3 | 1148.6 ± 24.0 | 1126.7 ± 42.6 | 1131.8 ± 43.8 | .014 | .093 | .697 |
| Cortical area (mm2) | 284.0 ± 27.0 | 282.7 ± 27.5 | 261.1 ± 31.3 | 257.3 ± 29.5 | .008 | .076 | .237 |
| Cortical thickness (mm) | 5.2 ± 0.5 | 5.1 ± 0.5 | 4.7 ± 0.6 | 4.7 ± 0.6 | .011 | .169 | .475 |
| Peripheral circulation (mm) | 71.5 ± 4.0 | 71.6 ± 3.6 | 70.3 ± 4.1 | 70.1 ± 3.9 | .228 | .663 | .419 |
| Polar moment of inertia (mm4) | 24,442 ± 5039 | 24,212 ± 4910 | 22,231 ± 4544 | 21,925 ± 3992 | .110 | .127 | .929 |
| Stress-strain index (mm3) | 1590 ± 525 | 1600 ± 239 | 1423 ± 253 | 1425 ± 239 | .025 | .774 | .412 |
| Muscle area (mm2) | 6894 ± 1093 | 6707 ± 1025 | 6523 ± 1125 | 6438 ± 1010 | .112 | .098 | .300 |
| Fat area (mm2) | 5218 ± 1439 | 4856 ± 1606 | 5663 ± 1750 | 4892 ± 1454 | .544 | <.001 | .034 |
a
Mean ± SD.
b
A two-factor repeated-measures ANOVA was performed with time (0, 6, and 12 months) and diet (HP or NP) as independent variables.