Table 5.
Summary of VOCs detected in headspace of culture medium after two week incubation
| Compound | OUS-11-2w | WI-38 VA13-2w | DMEM | A549-2w | A549 vs. OUS-11 | A549 vs. WI-38 VA13 | A549 vs. DMEM | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Average (μM) |
SD | Average (μM) |
SD | Average (μM) |
SD | Average (μM) |
SD |
p-value (ANOVA) |
Ratio (A549/OUS-11) |
p-value (ANOVA) |
Ratio (A549/WI-38 VA13) |
p-value (ANOVA) |
Ratio (A549/DMEM) |
|
| 2-Butanone | 4.293 | 0.184 | 8.971 | 0.761 | 0.767 | 0.120 | 14.616 | 0.570 | < 0.001 | 3.4 | 0.001 | 1.6 | < 0.001 | 19.1 |
| 2-Pentanone | 0.158 | 0.003 | 0.203 | 0.024 | 0.031 | 0.002 | 0.363 | 0.016 | < 0.001 | 2.3 | 0.001 | 1.8 | < 0.001 | 11.6 |
| 2-Hexanone | 0.030 | 0.000 | 0.033 | 0.000 | 0.034 | 0.002 | 0.037 | 0.002 | 0.008 | 1.2 | 0.039 | 1.1 | 0.150 | 1.1 |
| 2-Methylpyrazine | < LOD | 0.004 | 0.001 | 0.015 | 0.003 | 0.004 | 0.000 | < 0.001 | - | 0.750 | 1.0 | 0.005 | 0.3 | |
| Dimethyl Succinate | 0.043 | 0.000 | < LOD | < LOD | 0.052 | 0.001 | < 0.001 | 1.2 | < 0.001 | - | < 0.001 | - | ||
| Acetophenone | 0.245 | 0.004 | 0.311 | 0.015 | < LOD | 0.561 | 0.015 | < 0.001 | 2.3 | < 0.001 | 1.8 | < 0.001 | - | |
| Phenol | 0.077 | 0.006 | 0.120 | 0.005 | 0.031 | 0.001 | 0.129 | 0.005 | 0.001 | 1.7 | 0.144 | 1.1 | < 0.001 | 4.1 |
The VOC concentrations are shown with standard deviations. The p-values were calculated by ANOVA. The ratio is a comparison of average concentrations of A549 and each samples