Table 2.
Proteins up-regulated in EAE spinal cords determined by iTRAQ analyses.
| Fresh Frozen | Formalin Fixed Paraffin Embedded |
||||
|---|---|---|---|---|---|
| Protein Name | Accession Numbera |
iTRAQ Ratio (E/C)b |
p-valuec | iTRAQ Ratio (E/C)b |
p-valuec |
| Actin, cytoplasmic 1 | ACTB_RAT | 1.5 | 0.05 | 1.3 | 0.03 |
| Alpha-1-macroglobulin | A1M_RAT | 2.9 | 0.04 | 1.7 | 0.01 |
| Apolipoprotein E | APOE_RAT | 2.3 | 0.00 | 3.3 | 0.01 |
| Ceruloplasmin | CERU_RAT | 2.6 | 0.04 | 2.2 | 0.01 |
| Heat shock protein beta-1 | HSPB1_RAT | 1.8 | 0.03 | 2.5 | 0.00 |
| Hemopexin | HEMO_RAT | 1.9 | 0.02 | 3.5 | 0.00 |
| Histone H2B type 1 | H2B1_RAT | 2.0 | 0.01 | 2.2 | 0.02 |
| Plastin-2 | Q5XI38_RAT | 3.2 | 0.02 | 2.6 | 0.03 |
| Vimentin | VIME_RAT | 1.7 | 0.01 | 1.8 | 0.01 |
a
SwissProt accession number.
b
iTRAQ Ratio E/C denotes iTRAQ ratio of EAE/Control
c
p-values were derived via the 2-tailed Student's t-test for each protein by comparing the two EAE with the two control values using Excel (Microsoft, Redmond, WA).