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. 2012 Mar 26;7(3):e33855. doi: 10.1371/journal.pone.0033855

Table 1. Clinical features of the subjects included in the study.

		302_Beijing			Youan_Beijing			Guangxi
	HCC	CHB	P	HCC	CHB	P	HCC	CHB	P
Number	169	203		326	522		313	342
Age, y	50 (42, 55)	49 (38, 57)	0.37^a	52 (45, 58)	40 (34, 49)	<0.001^a	43 (37, 51)	41 (35, 52)	0.10^a
Gender (male/female)	143/26	158/45	0.10^b	270/56	379/143	<0.001^b	280/33	283/59	0.01^b
Smoking (Yes/No)	84/85	64/139	<0.001^b	135/159	103/378	<0.001^b	128/185	141/201	0.93^b
Drinking (Yes/No)	93/76	71/132	<0.001^b	141/153	113/366	<0.001^b	95/218	97/245	0.58^b
Family history of HBV (Yes/No)	98/71	133/70	0.14^b	141/172	333/169	<0.001^b
Family history of HCC (Yes/No)							52/261	16/326	<0.001^b
HbeAg (+/−)	65/104	131/72	<0.001^b	128/198	356/166	<0.001^b
ALT (IU/L)	218 (67, 227)	227 (113, 268)	<0.001^a	129 (109, 142)	131 (122, 143)	0.01^a
AST (IU/L)	158 (72, 230)	160 (96, 245)	0.03^a	124 (108, 165)	125 (109, 162)	0.88^a
TBil (µmol/L)	36 (19, 49)	34 (21, 50)	0.08^a	49 (28, 61)	39 (22, 54)	<0.001a
DBil (µmol/L)	28 (15, 35)	29 (15, 36)	0.89^a	33 (16, 50)	27 (11, 35)	<0.001^a
Log HBV-DNA (copy/mL)	5.9 (4.6, 6.2)	6.7 (5.5, 7.2)	<0.001^a	5.4 (4.6, 6.0)	5.6 (4.7, 6.1)	<0.001^a

Age, ALT, AST, TBil, DBil, and HBV-DNA as median (25-percentile, 75-percentile).

HCC: hepatocellular carcinoma.

CHB: chronic hepatitis B.

^aMann-Whitney U test.

^bChi-square test.