High fat diet increases gonadal white adipose tissue and mammary gland mass disproportionate to weight gain in female Aromhum mice. At the end of the 3-month diet treatment period, female Aromhum mice were sacrificed and their intact gonadal adipose tissue and fourth mammary glands were removed and weighed. (A) Average absolute mass of gonadal white adipose tissue. (B) Average mass of gonadal white adipose tissue relative to total body mass. Normal chow group, n=4; high fat group, n=4. *, P<0.05 (paired t test). (C) Average absolute mass of mammary glands. (D) Average mass of mammary glands relative to total body mass. Normal chow group, n=8; high fat group, n=7. **, P<0.01 (paired t test).