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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Leuk Res. 2012 Feb 17;36(5):619–624. doi: 10.1016/j.leukres.2012.01.020

Figure 4. KG-1 Leukemia Cells are Non-Permissive for MYXV Infection and Replication In Vitro but are Competent for Virus Binding.

Figure 4

(A) At 24 hours after MYXV treatment, THP-1 or KG-1 leukemia cells were evaluated for evidence of the early stages of MYXV infection (eGFP expression) by flow cytometry. The differentiating agent, PMA, was used in an attempt to augment permissiveness. (B) THP-1 or KG-1 leukemia cells were treated with MYXV and new infectious viral progeny production measured over time. Titers are expressed as log FFU/106 leukemia cells. The differentiating agent, PMA, was used in an attempt to augment viral permissiveness. (C) THP-1 or KG-1 cells were exposed to MYXV for 1 hour, washed extensively and the remaining cell-associated viral protein assessed by Western blotting.