Table 2.

Linear B-cell Epitope Prediction for BA21.Peptides and their sequences are shown, along with regions of each peptide identified to have the following antigenic properties: beta-turns, hydropathicity, exposed surfaces, charged (polar) regions, bulky regions (high molecular weight), hydrophobic regions, along with regions containing loops and other flexible structures. An antigenicity score was assigned to the regions with greatest antigenicity (High Antigenicity). Shaded regions represent the peptides with the greatest predicted overall reactivity with the darkest shading denoting the most reactive region of BA21.

PEPTIDE ID	PEPTIDE SEQUENCE
BA21.1	QEQCRFPNITNSHVSIL
BA21.2	QEQCRFPNITNSHVSILQER
BA21.3	NSHVSILQERPPLENRVLTGW
BA21.4	PPLENRVLTGWGLNWDLGLSQW
(−) DHBV Core	EEAEEIPLGDLFKHQEERI

	Q	E	Q	C	R	F	P	N	I	T	N	S	H	V	S	I	L	Q	E	R	P	P	L	E	N	R	V	L	T	G	W	G	L	N
EPITOPE FEATURE	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34
BETA-TURN																			X	X	X	X	X	X							X	X	X	X
HYDROPATHICITY	X	X	X	X	X													X	X	X	X	X	X	X
SURFACE				X	X	X	X	X	X	X	X	X	X			X	X	X	X	X	X	X	X	X	X	X	X			X	X	X	X	X
POLARITY																X	X	X	X	X	X	X	X	X	X	X	X				X	X	X	X
MOLECULAR WT		X	X	X	X	X	X										X	X	X	X	X								X	X	X	X	X	X
HYDROPHOBICITY																	X	X	X	X	X	X	X	X	X	X	X		X	X	X	X	X	X
FLEXIBILITY	X	X	X	X	X			X	X	X	X	X	X				X	X	X	X	X	X	X	X
LOW ANTIGENICITY
HIGH ANTIGENICITY																		X	X	X	X	X	X	X