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. Author manuscript; available in PMC: 2013 Apr 15.
Published in final edited form as: Free Radic Biol Med. 2012 Feb 4;52(8):1255–1263. doi: 10.1016/j.freeradbiomed.2012.01.029

Table 3.

Indices of peripheral nerve function in Zucker fatty and Zucker lean rats before and after acipimox treatment

Zucker lean Zucker lean + A Zucker fatty Zucker fatty + A
Before treatment
MNCV, m/s 53.9±0.8 53.6±1.0
SNCV, m/s 41.5±0.4 36.7±0.9**
Thermal response latency, s 14.6±0.9 21.2±1.4**
Tactile response thresholds, g 16.0±1.9 8.4±0.8**
Mechanical withdrawal thresholds, g 11.6±0.6 17.8±1.0**
After treatment
MNCV, m/s 54.9±0.7 53.4±0.5 54.1±0.7 54.9±1.3
SNCV, m/s 45.1±1.1 44.1±0.8 38.4±0.9** 44.1±0.8##
Thermal response latency, s 10.7±0.2 11.3±0.4 22.8±1.0** 16.5±0.5**,##
Tactile response thresholds, g 18.7±0.8 20.4±1.8 7.1±0.5** 8.9±0.3**
Mechanical withdrawal thresholds, g 10.5±0.6 11.2±0.5 16.3±0.7** 12.6±0.4**,**

Mean ± SEM, n = 7–9. A – acipimox.

**

p < 0.01 vs age-matched Zucker lean groups;

##

p < 0.01 vs Zucker fatty rats treated with acipimox