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. Author manuscript; available in PMC: 2013 Jun 5.
Published in final edited form as: Virology. 2012 Mar 3;427(2):208–216. doi: 10.1016/j.virol.2012.01.029

FIGURE 6. Expression of wildtype PKR but not PKZ enhances IFN-β induction by measles virus.

FIGURE 6

FIGURE 6

PKRkd HeLa cells were transfected with the indicated plasmids and at 15 h after transfection were either mock infected (−) or infected (+) with Cko virus. At 24 h after infection total RNA was prepared and IFN-β transcript levels normalized to GAPDH were determined using quantitative real-time PCR. (A) Representative induction results shown for one of three independent experiments normalized to vector-transfected, uninfected cells. (B) The mean induction of IFN-β mRNA and standard deviations determined for three independent experiments. The results are normalized to Cko-infected, transfected cells expressing WT PKR taken as 100%.