Fig. 1.

Protective effects of SAMC against CCl₄-induced hepatotoxicity. H&E staining on a control, b CCl₄ treatment, c SAMC treatment, and d CCl₄ + SAMC groups. CCl₄ treatment caused obvious centrilobular necrosis in the liver. However, no significant necrosis and inflammation are observed in control, SAMC treatment, and CCl₄ + SAMC groups. e CCl₄ exposure induced an increase in serum ALT level which was reversed by the pre-treatment of SAMC. Data presented are expressed as Mean ± SEM (n = 8–10) and experimental groups marked by different letters represented significant differences between groups at p < 0.05 (Kruskal–Wallis test followed by Dunns post hoc test). Bar equals 20 microns