Table 2. Details of the genes in which the SNPs used in this study were identified.
Gene | Abbr. | A/Z | nSNP | I/E | MAF | He | FST | Function | |
---|---|---|---|---|---|---|---|---|---|
Pigmentation | Micropthalmia-associated transcription factor | MITF | A | 2 | I | 0.10 | 0.20 | 0.006 | A critical regulator of pigment cell development and survival (Widlund and Fisher, 2003) |
Melanocortin-1 receptor | MC1R | A | 1 | E | 0.07 | 0.13 | 0.007 | Main role as a switch affecting the type of melanin pigment produced by the melanocytes (for example, Mundy et al., 2003) | |
Myosin-Va | MyoVA | A | 1 | I | 0.17 | 0.29 | 0.010 | Involved in transport of pigment-containing granules (melanosomes) to peripheral sites (Fukuda et al., 2002) | |
Pallidin | Pldn | A | 1 | I | 0.05 | 0.09 | 0.021 | Involved in the biogenesis of melanosomes (Falcón-Pérez and Dell'Angelica, 2002) | |
Tyrosinase-related protein-1 | TYRP1 | Z | 1 | I | 0.07 | 0.13 | 0.009 | Converts dopaquinone, a eumelanin and pheomelanin precursor, into eumelanin (April et al., 1998; Nadeau et al., 2007) | |
Vision | Rhodopsin | Rhod | A | 3 | I | 0.48 | 0.59 | 0.014 | A photoreceptor protein, which acts as a signal transducer in the rod outer segments of animal eyes. (Lamb, 1986) |
Ultraviolet-sensitive opsin | UV opsin | A | 1 | I | 0.42 | 0.43 | 0.116 | A visual pigment with its absorption maximum in the UV range. Forms the basis for UV vision (Yokoyama et al., 1998; Wilkie et al., 2000) | |
FM | Follistatin | FST | Z | 1 | E | 0.42 | 0.44 | 0.146 | A BMP antagonist, expressed in the growing feather bud (Patel et al., 1999) |
Other | 5-Aminolaevulinate synthase (Ala-synthase) | ALASY | A | 2 | I | 0.43 | 0.55 | 0.022 | The first and rate-controlling enzyme of haeme biosynthesis (Maguire et al., 1986) |
Aldolase-B | ALDOB | Z | 2 | I | 0.32 | 0.22 | 0.023 | An important enzyme for fructose and glucose metabolism (Ito et al., 1998) | |
CEPUS | CEPU | A | 1 | I | 0.16 | 0.25 | 0.021 | A secreted type of neural glycoprotein belonging to the immunoglobulin-like opioid-binding cell adhesion molecule (OBCAM) subfamily (Kim et al., 1999) | |
Transforming growth factor-β2 | TGFBb | A | 1 | I | 0.10 | 0.19 | 0.024 | Has a role in growth, development, repair, inflammation and immunity (Clark and Coker, 1998) | |
Tropomyosin | Tropom | A | 2 | I | 0.12 | 0.46 | 0.035 | Binds to actin filaments and regulates the interaction of the filaments with myosin in response to Ca2+ (Wegner, 1979) | |
Very low-density lipoprotein receptor | VLDR2 | Z | 1 | E | 0.32 | 0.42 | 0.026 | Associated with the metabolism of fat and cholesterol. Similar to the low-density lipoprotein (LDL) receptor (Takahashi et al., 1992) |
Abbreviations: A, autosomal gene; Abbr., abbreviation used in text; E, the SNP locus is in an exon of the gene; FM, feather morphogenesis-associated gene; He, expected heterozygosity; I, the SNP locus is in an intron in or near the gene; MAF, minor allele frequency; nSNP, number of SNPs in the gene region used in the study; Z, sex-linked gene. The haplotype frequencies of loci with more than one SNP are listed in Supplementary Appendix 3.