Table 2. Healing QTLs discovered in the MRL/lpr × C57BL/6NTac F2 intercross.
Chr | cM | −CI | +CI | SEX | Rsq | Full_LPR | a (LPR) | d (LPR) | Int | Int (s.e.) | a | a (s.e.) | d | d (s.e.) | a/s.d. | d/s.d. | MM | MB | BB | Name |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 101 | 93 | 106 | F | 0.074 | 2.36 | 0.10 | 2.91 | 0.57 | 0.04 | −0.01 | 0.04 | 0.22 | 0.07 | −0.03 | 0.56 | 0.56 | 0.79 | 0.58 | New |
4 | 66 | 62 | 79 | B | 0.049 | 3.07 | 3.09 | 0.90 | 0.73 | 0.03 | −0.11 | 0.03 | 0.08 | 0.05 | −0.28 | 0.22 | 0.63 | 0.82 | 0.84 | Heal8 |
8 | 51 | 42 | 73 | B | 0.060 | 3.74 | 4.44 | 0.14 | 0.77 | 0.03 | 0.11 | 0.03 | 0.01 | 0.04 | 0.30 | 0.04 | 0.88 | 0.78 | 0.65 | Heal1 |
9 | 60 | 48 | 74 | M | 0.077 | 2.32 | 0.10 | 2.95 | 0.74 | 0.04 | −0.01 | 0.04 | 0.24 | 0.07 | −0.03 | 0.62 | 0.73 | 0.98 | 0.75 | Sth9b |
11 | 55 | 46 | 72 | M | 0.116 | 3.57 | 4.28 | 0.07 | 0.84 | 0.04 | −0.17 | 0.04 | 0.01 | 0.05 | −0.43 | 0.03 | 0.67 | 0.85 | 1.00 | Heal10 |
12 | 13 | 0 | 19 | B | 0.033 | 2.01 | 2.26 | 0.57 | 0.79 | 0.03 | 0.08 | 0.03 | −0.04 | 0.04 | 0.20 | −0.11 | 0.87 | 0.75 | 0.71 | New |
13 | 30 | 21 | 37 | B | 0.067 | 4.22 | 3.81 | 1.48 | 0.81 | 0.03 | −0.10 | 0.03 | −0.08 | 0.04 | −0.27 | −0.21 | 0.71 | 0.73 | 0.91 | Heal7 |
16 | 12 | 3 | 22 | M | 0.082 | 2.48 | 1.74 | 1.86 | 0.77 | 0.04 | 0.10 | 0.04 | 0.17 | 0.07 | 0.26 | 0.44 | 0.87 | 0.94 | 0.67 | Heal11 |
18 | 24 | 0 | 36 | B | 0.022 | 1.35 | 1.84 | 0.33 | 0.79 | 0.03 | −0.07 | 0.03 | −0.03 | 0.05 | −0.19 | −0.09 | 0.72 | 0.76 | 0.87 | Heal9 |
18 | 43 | 0 | 47 | F | 0.067 | 2.13 | 0.01 | 2.74 | 0.77 | 0.04 | 0.00 | 0.04 | −0.18 | 0.06 | 0.00 | −0.47 | 0.77 | 0.58 | 0.77 | Heal9 |
Abbreviations: a, additive; Chr, chromosome; (−) and (+) CI, proximal and distal confidence interval limits; cM, QTL centiMorgan location; d, dominance; Full, LPR for full model; Int, intercept; MM, MB, BB, mean phenotype for the respective genotypes with M for MRL allele and B for C57BL/6 allele; Logarithm of Probability (LPR), −log10(Prob); Name, Previous designation or new if the QTL was unreported before; Rsq, r-squared; Sex, (M)ale, (F)emale, (B)oth.
Significant results are in bold face font.