Table 1.
dye | *Peak area reduced x2 | *Peak area slope | *Peak height reduced x2 | *Peak height slope | Concentration detection limit | Mass detection limit | Average theoretical plate count | Spectral cross-talk |
---|---|---|---|---|---|---|---|---|
BODIPY | 0.10 | 1.01 ± 0.01 | 0.10 | 1.01 ± 0.03 | 20 ± 7 pM | 1.4 ± 0.4 zmol | 5.0 ± 0.4 × 105 | 1.4% |
tetramethyl-rhodamine | 0.94 | 1.02 ± 0.01 | 0.88 | 1.02 ± 0.02 | 10 ± 2 pM | 600 ± 100 ymol | 6.0 ± 1.0 × 105 | 0.0004% |
Reduced X2 and slope are from a plot of log concentration vs. log signal. In calculating the reduced X2 statistic, propagation of errors was used to estimate the uncertainty in the signal, starting with the standard deviation of the mean of three replicate injections.
Capillary dimensions: 40 cm length and 20-μm inner diameter. Separation voltage =18 kV. Injection voltage = 1 kV. Injection time = 1 s. Injection volume ~10 pL. Analyte concentration ranged from 50 pM to 10 μM for tetramethylrhodamine and from 100 pM to 10 μM for BODIPY.