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. Author manuscript; available in PMC: 2012 Aug 6.
Published in final edited form as: Lancet. 2011 Jul 21;378(9790):507–514. doi: 10.1016/S0140-6736(11)60825-8

Table 3.

H. pylori eradication by treatment arm for three definitions of analysis population


Analysis Population N Eradicated
95% CI for Percent Eradicated Difference from Standard Arm Adjusted 95% CI for Difference
N Percent
Intention to Treat (ITT) 1463

14-day Standard 488 401 82.2% 78.5%, 85.5% (referent)
5-day Concomitant 489 360 73.6% 69.5%, 77.5% 8.6% 2.6%, 14.5%
10-day Sequential 486 372 76.5% 72.5%, 80.2% 5.6% −0.4%, 11.6%

Definitive 6-week UBT 1414

14-day Standard 475 401 84.4% 80.8%, 87.6% (referent)
5-day Concomitant 471 360 76.4% 72.3%, 80.2% 8.0% 2.2%, 13.7%
10-day Sequential 468 372 79.4% 75.5%, 83.1% 4.9% −0.9%, 10.8%

Adherent to Therapy 1314

14-day Standard 434 378 87.1% 83.6%, 90.1% (referent)
5-day Concomitant 442 348 78.7% 74.6%, 82.5% 8.4% 2.7%, 14.0%
10-day Sequential 438 355 81.1% 77.1%, 84.6% 6.0% 0.3%, 11.8%