Table 5.

Effect of Muscadine Grape Seed Supplementation on Markers of Lipid Peroxidation and Antioxidant Capacity

	Placebo			MGS Supplement			MGS vs Placebo**
	Baseline	Follow-up		Baseline	Follow-up
Marker	Mean (SEM)	Mean (SEM)	p Value*	Mean (SEM)	Mean (SEM)	p Value*	p Value
MDA, μM	0.50 (0.04)	0.43 (0.03)	0.05	0.54 (0.03)	0.44 (0.03)	0.01	0.61
8-isoprostane, pg/mL	152.7 (11.0)	179.7 (12.0)	0.002	157.0 (11.4)	161.9 (11.8)	0.64	0.08
Total antioxidant capacity, mM†	0.65 (0.01)	0.66 (0.01)	0.86	0.65 (0.01)	0.65 (0.01)	0.85	0.80

^*Least squares means contrast from the mixed linear model.

^**Test of treatment effect in the mixed linear model.

^†mM uric acid equivalents.

MGS = muscadine grape seed; MDA = malondialdehyde.