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Mass spectrometer modalities commonly used in proteomic research. A mass spectrometer consists of three modules: 1) an ion source (ESI or MALDI), which ionizes the peptides to be analyzed, 2) a mass analyzer (or a combination of analyzers), which can be used as a collision cell for fragmentation and/or sort the ions by their mass-to-charge ratio, and 3) a detector which amplifies and quantifies the resulting signal.
