Table 1.

m102.4 concentrations and half-life in African green monkeys.

	AGM 11	AGM 2	AGM 3	AGM 41
Total	50 mg	50 mg	10 mg	10 mg
Dose	11.1 mg/kg	11.0 mg/kg	2.5 mg/kg	2.6 mg/kg
Day	μg/ml
02,3	501.1	513.7	117.6	88.9
1	222.3	351.7	57.1	22.5
3	180.7	356.3	47.3	36.7
6	90.0	85.2	27.1	21.8
12	61.8	50.3	17.5	12.2
24	25.4	29.1	7.6	7.6
36	6.8	9.4	2.8	3.9
48	6.8	5.1	2.7	1.9
Half-life	Days
t1½	.85	1.83	.96	.50
t2½	10.2	10.3	11.7	12.5
	mg*h/L
AUC	59910	73828	17230	13503
Mean AUC	66,869		15,367

¹male;

²m102.4 infusion;

³serum collected post-infusion;

Abbreviations: distribution half-life time (t1_1/2), elimination half-life time (t2_1/2), area under curve (AUC).