Table 2.
AGM # | day 0a | day 3a | day 6 | day 10 | day 13 | day 16 |
---|---|---|---|---|---|---|
Control | ||||||
13b | 0.0 | 0.0 | 0.0 | * | * | * |
17b | 0.0 | 0.0 | 0.1 | * | * | * |
10 hr/d3d | ||||||
14 | 3.0 | 934.8 | 1152.4 | 802.5 | 586.3 | 484.0 |
15 | 0.0 | 642. | 903.2 | 604.9 | 583.3 | 310.6 |
16 | 2.5 | 957.4 | 1344.1 | 830.3 | 600.1 | 458.5 |
18 | 0.0 | 381.3 | 372.0 | 406.8 | 123.8 | 84.7 |
24hr/d3d | ||||||
19 | 0.0 | 423.5 | 406.9 | 345.0 | 252.8 | 178.4 |
20 | 0.0 | 519.1 | 612.9 | 351.6 | 230.2 | 106.4 |
21 | 2.1 | 543.7 | 647.7 | 299.9 | 42.9 | 72.6 |
22 | 0.0 | 528.9 | 690.2 | 406.7 | 27.4 | 11.2 |
72hr/d5d | ||||||
23 | 0 | 0 | 1581.9 | 695.2 | 118.2 | 11.7 |
24 | 9.4 | 0 | 624.8 | 575.0 | 239.2 | 96.7 |
25 | 0.0 | 2.3 | 828.7 | 527.7 | 197.5 | 158.7 |
26 | 0.0 | 3.5 | 951.0 | 534.7 | 305.1 | 316.6 |
sample collected before infusion;
succumbed to disease on day 8;
each animal received two 100 mg doses as indicated;
not sampled.