Table 3.

Weight Losses From Randomized Trials That Evaluated Selected Commercial Weight Loss Programs

Program Study	N	Intervention	Mean Weight Change	Mean Weight Change at Long- Term Follow-Up	Attrition	Attrition at Long-Term Follow-Up
Jenny Craig
Rock et al¹²⁶	70 (100% F)	Center-based Jenny Craig	−7.2 kg at 6 mo^a	−7.3 kg at 12 mo^a	0% at 6 mo	9% at 12 mo
		Usual care (2 meetings with dietitian and print materials)	−0.3 kg at 6 mo^b	−0.7 kg at 12 mo^b	0% at 6 mo	6% at 12 mo
Rock et al¹²⁷	442 (100% F)	Center-based Jenny Craig	−10.1 kg at 12 mo^a	−7.4 kg at 24 mo^a	5% at 12 mo	10% at 24 mo
		Telephone-based Jenny Craig	−8.5 kg at 12 mo^a	−6.2 kg at 24 mo^a	4% at 12 mo	7% at 24 mo
		Usual care (2 individual counseling sessions and monthly contacts)	−2.4 kg at 12 mo^b	−2.0 kg at 24 mo^b	9% at 12 mo	7% at 24 mo
Nutrisystem
Foster et al¹²⁸	69 (71% F)	Nutrisystem D+group behavioral treatment for 24 wk	−7.1% at 12 wk^a	−9.7% at 24 wk	14% at 24 wk	N/A
	100% T2D	Diabetes Support and Education for 12 wk, then Nutrisystem D+group behavioral treatment for 12 wk	−0.4% at 12 wk^b	−5.3% at 24 wk	18% at 24 wk
Weight Watchers
Djuric et al¹²⁹^*	48 (100% F)	Usual care	+0.9 kg at 12 mo^a	N/A	19% at 12 mo	N/A
		Weight Watchers	−2.6 kg at 12 mo^a
		Individual counseling	−8.0 kg at 12 mo^b
		Weight Watchers+individual counseling	−9.4 kg at 12 mo^b
Heshka et al^41,130	423 (85% F)	Weight Watchers	−4.3 kg at 12 mo^a	−2.9 kg at 24 mo^a	20% at 12 mo	25% at 24 mo
		Self-help (with 2 dietitian visits)	−1.3 kg at 12 mo^b	−0.2 kg at 24 mo^b	17% at 12 mo	29% at 24 mo
Jebb et al¹³¹	772 (87% F)	Weight Watchers	−4.06 kg at 12 mo^a	N/A	42% at 12 mo	N/A
		Usual care	−1.77 kg at 12 mo^b

All studies were analyzed using an intention-to-treat population, except as indicated by an asterisk (*), in which case a completers population was examined.

Different letters (in superscript) indicate statistically significant differences between groups.

F indicates female; N/A, not applicable; T2D, type 2 diabetes.

Adapted from Webb et al.¹²²