Table 3.
Previously reported cancer susceptibility alleles on 8q24 and bladder cancer riska
| Allele |
MAF |
LD with rs2294008 |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| SNP | Position | Major | Minor | Case | Control | OR (95% CI) |
P-value | D′ | Reported cancer association |
| rs10505483b | 128194377 | G | A | 0.031 | 0.029 | 1.08 (0.75–1.56) |
0.688 | 0.02 | Prostate |
| rs13281615 | 128424800 | A | G | 0.414 | 0.412 | 1.01 (0.89–1.15) |
0.868 | 0.03 | Breast |
| rs6983267 | 128482487 | C | A | 0.491 | 0.487 | 1.02 (0.89–1.15) |
0.815 | 0.01 | Prostate, colorectal |
| rs1447295 | 128554220 | C | A | 0.102 | 0.086 | 1.21 (0.97–1.50) |
0.090 | 0.07 | Prostate |
| rs9642880 | 128787250 | G | T | 0.488 | 0.457 | 1.14 (1.06–1.22) |
2.1 × 10−4 | 0.01 | Bladder |
Results for rs9642880 were from all US populations; results of other SNPs were from discovery phase population.
rs10505483 is in complete LD with rs16901979.