Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jan 3;21(8):1770–1781. doi: 10.1093/hmg/ddr610

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2012. Published by Oxford University Press

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 6. — Autophagy is inhibited at advanced stages of MSD liver pathology. (A) LC3 immunoblots on total liver homogenates from MSD (n= 3) and control mice (n= 3) at P15, 1 month and 3 months. Autophagosome accumulation is expressed as the fold change of the LC3-II/actin ratio compared with control; **P < 0.01, ***P < 0.005. (B) Levels of BECN-1 were measured in liver extracts from MSD (n= 3) and control mice (n= 3) at P15, 1 month and 3 months. The BECN-1/actin ratio is expressed as fold changes; **P < 0.01. (C) Becn1 mRNA levels were determined by real-time PCR in liver samples (n= 3) at 3 months.