Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Polydactyly phenotype information
| Genotype | Number of embryos | Normal (%) | Broad digit 1 in the absence of ectopic digit (%) | Ectopic digit(s) (%) |
|---|---|---|---|---|
| WT | 10 | 100 | 0 | 0 |
| Zic3 null | 8 | 100 | 0 | 0 |
| Gli3+/− | 22 | 0 | 0a | 100 |
| Zic3 null;Gli3+/− | 10 | 60 | 30 | 10 |
| Gli3−/− | 8 | 0 | 0 | 100 |
| Zic3 null;Gli3−/− | 8 | 0 | 0 | 100 |
a50% of Gli3 +/− embryos had broad digit 1 on the forelimb (see Supplementary Material, Fig. S4), but 100% had ectopic digits on the hindlimb.
