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Summary of tissular BACE1 changes in the context of AD.
| Tissue | BACE1 Changes | Technique | References |
|---|---|---|---|
| Post-mortem brain | Levels increased by ~30% in AD | ELISA/Western blot | [19, 20, 27] |
| CSF | Levels increased in MCI, no change in AD | ELISA/Western blot | [18] |
| Blood platelets | Decreased intensity of the 37 kDa band in AD | Western blot | [46, 48] |
| PBMC | Not reported | ||
| Red blood cells | Not reported | ||
| Plasma/Serum | Not reported | ||
| Other tissues | Not reported |
