Table 2. Within-group brain activation to food versus non-food images in women with restricting anorexia nervosa and women with binge-purging anorexia nervosa.
Brain regions | BA | Laterality | x | y | z | Cluster Size (voxels) | Cluster P |
Food>Non-Food | |||||||
RAN (n = 11) | |||||||
Cerebellar Vermis | – | L | −25 | −66 | −16 | 41 | 0.001 |
Visual Cortex | 18 | L | −14 | −83 | −7 | 50 | 0.001 |
DLPFC | 9 | R | 40 | 5 | 24 | 66 | 0.002 |
Medial PFC | 8 | — | 0 | 42 | 40 | 179 | 0.0006 |
BPAN (n = 7) | |||||||
Cerebellar Vermis | — | L | −4 | −56 | −27 | 111 | 0.0008 |
Cerebellar Vermis | — | R | 25 | −62 | −14 | 389 | 0.0002 |
Inferior Temporal Gyrus | 20 | R | 22 | −6 | −44 | 124 | 0.0009 |
Talairach Coordinates = x, Saggital plane, y, Coronal plane, z, Axial plane; Cluster size in voxels, each voxel equals 3.75 mm×3.75 mm×3 mm; Cluster p = cluster probability corrected at the level of one false positive or less. ABBREVIATIONS: BA = Brodmann's Area; Laterality = L, Left, R, Right; p = probability; AN = Anorexia Nervosa, RAN = Restricting Anorexia Nervosa, BPAN = Binge Purge Anorexia Nervosa, HC = Healthy Controls; DLPFC = Dorsolateral Prefrontal Cortex, SMA = Supplementary Motor Area. Note. Healthy control and total AN group data published in Brooks et al., (2011), PLoS One.