Figure 5. Effects of palmitate and ISV on gene expression.

After 72 h of treatment with or without 0.5 mM palmitate (Pal) in the presence or absence of ISV 10⁻⁸ M and 10⁻⁶ M, gene expression levels in α-TC1–6 cells were determined and normalized to Hprt. Data is expressed as relative level to control (n = 10–12 samples in each group, RNA extracted from three independent experiments). *P<0.05, **P<0.01, *** P<0.001 vs. control. ^#P<0.05, ^##P<0.01 vs. 0.5 mM Pal.