Table 1.
Annotation of genes encoded by the e14 element. The functional annotation of the e14 genes along with the BLAST and FASTA hits, the closest structural homolog if any and the cluster to which the gene belongs are listed. TM indicates the transmembrane region, SS presence of signal sequence, COG, SM, PF, IPR, PS are prefixes to COG, SMART, PFAM, INTERPRO and PROSITE ids respectively. Genes for which direct or indirect evidence for transcriptional or translational expression is available have been indicated with a (+) sign and those genes which are inducible on SOS induction are marked with a (l+) in the last column of the table
| Name | Blattner number | Location | Protein length (orientation) | %G+C | Domain architecture and features | Function/similarity (Expression) |
| YmfD | b1137 | 659–1324 | 221 (-) | 0.35 | IPR001601 | Very weak match to Methyltranferase and tellurite resistance TehB (l+) |
| YmfE | b1138 | 1325–2029 | 234 (-) | 0.31 | TM(22–42, 59–79, 154–174, 186–206) | (l+) |
| Lit | b1139 | 2487–3380 | 297 (+) | 0.37 | PS00142 TM (61–82, 149–178) | T4 exclusion, Interacts with DNA, is a protease (l+) |
| IntE | b1140 | 3471–4598 | 375 (-) | 0.45 | IPR002104, PF00589 | phage integrase (l+) |
| Vxis | b1141 | 4579–4824 | 81 (-) | 0.44 | - | phage excisionase (l+) |
| YmfH | b1142 | 4861–5172 | 103 (-) | 0.54 | TM(42–62, 73–93) | similar to Q8FET3 of E. coli O6 (l+) |
| YmfI | b1143 | 5289–5630 | 113 (+) | 0.39 | - | (l+) |
| YmfJ | b1144 | 5568–5852 | 94 (-) | 0.47 | - | similar to Zinc finger protein Q8BGS3 (l+) |
| YmfK | b1145 | 6051–6725 | 224 (-) | 0.44 | IPR006198, PF00717 | cI/c2 repressor (l+) |
| b1146 | b1146 | 6513–7016 | 167 (+) | - | - | probable homolog of cro from Shigella flexneri (+) |
| YmfL | b1147 | 7048–7617 | 189 (+) | 0.49 | - | - |
| YmfM | b1148 | 7614–7952 | 112 (+) | 0.50 | - | - |
| YmfN | b1149 | 7962–9329 | 455(+) | 0.54 | IPR005021, PF03354, COG4626, SM00345 | Fusion of a replicase and a phage terminase |
| YmfR | b1150 | 9341–9523 | 60 (+) | 0.60 | TM(5–25, 26–46) | - |
| YmfO | b1151 | 9523–9934 | 137 (+) | 0.56 | IPR006944, PF04860 | Probable pseudogene, phage portal |
| YmfP | b1152 | 9935–10714 | 259 (+) | 0.58 | - | tail protein (baseplate?) |
| YmfQ | b1153 | 10705–11289 | 194 (+) | 0.57 | SS(1–32) | tail protein (baseplate?) |
| YcfK | b1154 | 11293–11922 | 209 (+) | 0.50 | COG3299 | tail fibre |
| YmfS | b1155 | 11924–12337 | 137 (+) | 0.42 | PF02413, IPR003458 | tail fibre assembly |
| TfaE | b1156 | 12309–12911 | 200 (-) | 0.48 | PF02413, IPR003458 | tail fibre assembly |
| StfE | b1157 | 12911–13411 | 166 (-) | 0.47 | - | side tail fibre |
| PinE | b1158 | 13477–14031 | 184 (+) | 0.49 | PF00239, PF02796, PS00397, PS00398 | DNA invertase – catalyses the inversion of 1800 bp P-region (+) |
| McrA | b1159 | 14138–14971 | 277 (+) | 0.38 | SM00507, IPR002711, IPR003615 | Modified cytosine restriction endonuclease A (+) |