Fig. 8.
Apoptosis and cell viability as estimated by flow cytometry after culturing. 200,000 cells per well with 50 μg ml−1 nanodiamonds in MEM containing 10% FCS were cultured for 24 h on a 24-well plate. After washing with 250 μl PBS, cells were labeled with propidium iodide and Annexin V-FITC (1:100). Among the apoptotic dye-positive cells, Annexin V-FITC labeled cells were plotted as early apoptotic cells and propidium iodide + Annexin-V-FITC labeled cells were plotted as late apoptotic cells. Unlabeled (non-apoptotic) cells were plotted for cell viability. *P < 0.05 vs. serum-only or PBS control.