Table 2.
Baseline levels of IGF-1 and IGF-1/IGFBP-3 in subgroups with different characteristics.
| Characteristics | Number | Mean (SD) | ||
|---|---|---|---|---|
| IGF-1 (ng/ml) | IGF-1/IGFBP-3 (molar ratio) | |||
| Gender | Males | 66 | 139 (45) | 0.151 (0.038) |
| Females | 77 | 112 (36) | 0.124 (0.039) | |
| p-valuea | <0.0001 | <0.0001 | ||
| Age | 50-59 | 53 | 141 (46) | 0.150 (0.044) |
| 60-69 | 55 | 119 (36) | 0.132 (0.037) | |
| 70-80 | 35 | 108 (38) | 0.122 (0.034) | |
| p-value | 0.001 | 0.003 | ||
| Center | Los Angeles, CA | 26 | 137 (54) | 0.148 (0.049) |
| Oakland, CA | 30 | 126 (38) | 0.146 (0.043) | |
| San Antonio, TX | 38 | 118 (40) | 0.132 (0.040) | |
| San Luis Valley, CO | 49 | 122 (40) | 0.128 (0.032) | |
| p-value | 0.3 | 0.1 | ||
| Race/ethnicity | White | 59 | 126 (41) | 0.135 (0.039) |
| Black | 34 | 132 (49) | 0.152 (0.047) | |
| Hispanic | 50 | 117 (39) | 0.127 (0.033) | |
| p-value | 0.2 | 0.02 | ||
| BMI | Normal (<25) | 56 | 127 (37) | 0.142 (0.037) |
| Overweight (25-30) | 53 | 133 (47) | 0.143 (0.043) | |
| Obese (>30) | 33 | 107 (40) | 0.118 (0.038) | |
| p-value | 0.02 | 0.01 | ||
| Smoking | Never | 62 | 131 (45) | 0.140 (0.041) |
| Former | 63 | 118 (41) | 0.132 (0.041) | |
| Current | 18 | 120 (36) | 0.137 (0.034) | |
| p-value | 0.2 | 0.5 | ||
| Previous polyps | No | 130 | 126 (43) | 0.139 (0.041) |
| Yes | 13 | 109 (30) | 0.114 (0.027) | |
| p-value | 0.08 | 0.04 | ||
a
p-value for Wilcoxon/Kruskal-Wallis test