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Osteocalcin secretion by encapsulated MC3T3-E1 cells in alginate beads cultured under dynamic conditions in (A) standard and (B) osteogenic medium for 16 days. (* denotes statistical significance (p < 0.05) compared with the 2-200 bead group and all other groups. ** denotes statistical significance (p < 0.05) compared with the 2-100 bead group and 1 wt. % groups).
