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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Dec 7;1819(9-10):1035–1054. doi: 10.1016/j.bbagrm.2011.11.009

Figure 4.

Figure 4

Binding of IF2mt to the E. coli ribosome. This image was taken from the cryo-EM structure of the 70S:mRNA:fMet-tRNA:IF2mt:GDPNP complex [63] and shows the orientation of IF2mt on the E. coli ribosome. The bacterial 30S subunit is shown in light yellow and the bacterial 50S subunit is shown in blue. Defining features of each subunit are labeled, including the head, shoulder and spur of the small subunit and the central protuberance and L7/L12 stalk base on the large subunit. IF2mt is shown in red, and the initiator tRNA is shown in green. The authors thank Dr. Rajendra Agrawal, Wadsworth Center, New York State Dept. of Health, Albany, NY for the cryo-EM image.