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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Psychopharmacology (Berl). 2011 Oct 1;220(4):673–685. doi: 10.1007/s00213-011-2516-9

Figure 6.

Figure 6

Effects of the M1 agonist 77-LH-28-1 as pretreatment to cocaine in Swiss-Webster mice. Leftmost panels show 77-LH-28-1 doses tested with 10 mg/kg cocaine, right panels show rightward shifts in the cocaine dose-effect function after administration of 3.2 mg/kg 77-LH-28-1. Abscissae, left panels: dose 77-LH-28-1 in mg/kg, “V” indicates vehicle; right panels: dose cocaine in mg/kg, “Sal” indicates saline. Ordinates: percentage cocaine-appropriate responses (top); response rate in responses per second (bottom). Data are groups means ± one S.E.M., N=8 (left), N=6 (right).

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