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. 2011 Nov 10;90(3):168–175. doi: 10.2471/BLT.11.092056

Table 3. Association between mother-to-child transmission of HIV and antiretroviral regimens taken in pregnancy, KwaZulu-Natal, South Africa, 2008–2009 (n = 2858) .

Regimena Infants with anti-HIV antibodiesb
OR 95% CI P
No. tested by PCR Found PCR-positive for HIV DNA
No. %
No antiretroviral prophylaxisc 68 11 16.2
Nevirapine alone 242 32 13.2 0.78 0.32–1.9 0.58
Zidovudine alone 63 2 3.2 0.17 0.04–0.78 0.02
Nevirapine and zidovudine 2089 118 5.7 0.30 0.14–0.66 0.003
Lifelong ART 396 20 5.1 0.27 0.11–0.68 0.006

ART, antiretroviral treatment; CI, confidence interval; DNA, desoxyribonucleic acid; HIV, human immunodeficiency virus; OR, odds ratio; PCR, polymerase chain reaction.

a Mothers were allocated to regimen groups irrespective of the reported duration of each antiretroviral intervention.

b The infants tested were aged 4–8 weeks.

c Reference category.