Table 2.

Helminth infections associated with marked and/or persistent eosinophilia

Parasitic Disease Organism(s)	Development and duration of Eosinophilia		Main anatomical site(s)	Diagnosis
	Acute	Persistent
Angiostrongyloidiasis
Angiostrongylus cantonensis	+		CNS	Larvae in CSF
Angiostrongylus costaricensis	+		GI	Biopsy
Ascariasis	+		GI	Eggs in stool
Clonorchiasis	+	+	Hepatobiliary	Eggs in stool, serology
Fascioliasis	+	+	Hepatobiliary	Eggs in stool, serology
Fasciolopsiasis	+		GI	Eggs in stool
Filarial infections
Lymphatic Filariasis
Brugia, Wuchereria	+	+	Blood, lymphatics	Mf in blood, serology, CFA
Loa loa*	+	+	Subcutaneous, eye	Mf in blood, worm extracted
Mansonella ozzardi*	+	+	Blood	Mf in blood
Mansonella perstans *	+	+	Blood, body cavities	Mf in blood, adult in tissue
Mansonella streptocerca*	+	+	Skin, subcutaneous tissue	Mf in skin snips
Onchocerca volvulus*	+	+	Skin, eye, subcutaneous tissue	Mf in skin snips, adults in nodules
Tropical pulmonary eosinophilia*	+	+	Lung	Serology
Gnathostomiasis	+	+	Soft tissue	Serology, worm in specimen
Hookworm*	+	+	GI, lung (acutely)	Eggs in stool
Opisthorchiasis	+	+	Hepatobiliary	Eggs in stool
Paragonimiasis	+	+	Lung, CNS, subcutaneous	Eggs in sputum, BAL, stool
Schistosomiasis	+			Serology
Schistosoma haematobium	+		Urinary tract	Eggs in urine
Schistosoma intercalatum	+		Hepatic, GI	Eggs in stool
Schistosoma japonicum	+		Hepatic, GI	Eggs in stool
Schistosoma mansoni	+		Hepatic, GI	Eggs in stool
Schistosoma mekongi	+		Hepatic, GI	Eggs in stool
Strongyloidiasis	+	+	GI, lung, skin	Larvae in stool, serology
Trichinosis	+	+	GI, muscle	Serology, muscle biopsy
Visceral larva migrans*
Toxocara canis; T catis	+	+	Liver, eye, lung	Serology, larvae in tissue
Baylisascaris procyonis	+	+	CNS, eye	Larvae in specimen