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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Semin Hematol. 2012 Apr;49(2):149–159. doi: 10.1053/j.seminhematol.2012.01.006

Table 3.

Types of Drug Reactions Associated with Eosinophilia

Manifestations Commonly Associated Drugs
Asymptomatic Penicillins, cephalosporins
Soft tissue swelling GM-CSF, IL-2
Pulmonary infiltrates Nonsteroidal anti-inflammatory agents
Interstitial nephritis Semisynthetic penicillins, cephalosporins
Myocarditis Ranitidine
Hepatitis Semisynthetic penicillins, tetracyclines
Hypersensitivity vasculitis Allopurinol, phenytoin
Gastroenterocolitis Nonsteroidal anti-inflammatory agents
Asthma, nasal polyps Aspirin
Eosinophilia-myalgia syndrome L-tryptophan contaminant
DRESS Sulfasalazine, hydantoin, carbamazepine, allopurinol, hydrochlorothiazide, cyclosporine, nevaripine